Describe the pathophysiology of gout.

Advanced Pathophysiology Walden University| NURS 6501 – Advanced Pathophysiology | Walden University

Gout, a form of inflammatory arthritis, is caused by the formation of uric acids crystals in joints and other tissues. Uric acid is an unwanted product that results from the body’s breakdown of purines. Purines are natural substances found in food and cells. Uric acid dissolves in blood, and is excreted by the kidneys. People with gout may have too much uric Acid in their bodies or they cannot eliminate it as efficiently. In this case, uric crystals can form.

The immune system triggers an inflammatory response when these crystals are present in the joints. This causes inflammation and can cause pain, swelling and redness. Repeated episodes of gout may lead to arthritis and joint damage. Gout usually affects the big and middle toes. But it also can happen in the knees, elbows and ankles. High blood pressure, diabetes and obesity are all risk factors for gout.

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